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Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice


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Shuai Jin

State Key Laboratory of Plant Cell and Chromosome Engineering, Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.University of Chinese Academy of Sciences, Beijing 100864, China.

Yuan Zong

State Key Laboratory of Plant Cell and Chromosome Engineering, Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.University of Chinese Academy of Sciences, Beijing 100864, China.

Qiang Gao

State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.

Zixu Zhu

State Key Laboratory of Plant Cell and Chromosome Engineering, Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.University of Chinese Academy of Sciences, Beijing 100864, China.

Yanpeng Wang

State Key Laboratory of Plant Cell and Chromosome Engineering, Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.

Peng Qin

Rice Research Institute, Sichuan Agricultural University, Chengdu 611130, China.

Chengzhi Liang

University of Chinese Academy of Sciences, Beijing 100864, China.State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.

Daowen Wang

State Key Laboratory of Plant Cell and Chromosome Engineering, Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.University of Chinese Academy of Sciences, Beijing 100864, China.

Jin-Long Qiu

State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

Feng Zhang

Department of Plant and Microbial Biology, Center for Plant Precision Genomics, The Microbial and Plant Genomics Institute, University of Minnesota, Minneapolis, MN 55108, USA.

Caixia Gao

State Key Laboratory of Plant Cell and Chromosome Engineering, Center for Genome Editing, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.University of Chinese Academy of Sciences, Beijing 100864, China.

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